:  

() , ( ), . . (, ) "-", , "-", (, ). - (Treg) .

,

, . CD103, -, , -. CD103+ - (ATRA) TGFb, -.

ATRA , , ATRA. TGFb - . ATRA Treg a4b7 CR9. MAdCAM-1 CCL25, - . , ATRA Treg "" . , IL-10 . .

" ", , , . , , ATRA TGFb, , . (TSLP), , IL-12 , Th2- . - . - TLR- TSLP, IL-25 IL-33, , Th2-, . , , .

 

 

 

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- 05/01/2015