:  

-

, - (Treg) - , , , . Treg . Treg, , "" (nTreg). Treg, -, , (iTreg).

Treg CD4, CD25, IL-2. Treg Forkhead box P3 (FoxP3).

FoxP3 - . , FOXP3  , , IPEX (Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked) - "- , , ".  scurfy.

Treg , CD4+ CD8+ T-, - . Treg , ,  TGF-β IL-10  . Treg CD152 (CTLA-4)  GITR (glucocorticoid-induced TNF receptor, - ), - .

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- 12/01/2015