:  

1 - , -, - - . . 1 5-10% . , , (GAD), IA-2 (- 2) ZnT8 ( 8). , 1 .

- - . , , - -. - Th1-, CD8+ - .

1 - . 1 6p21 30-50% . HLA-DRB1 HLA-DQB1. - DR3-DQA1*0501-DQB1*0201 (DR3) DR4-DQA1*0301-DQB1*0302 (DR4). , 40 -HLA , , CTLA-4, PTNP22, IL-2RA and IF1H1.

 

 

 

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- 05/09/2014